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Sharma HS, Cervos-Navarro J, Dey PK

Besides metabolite detoxification, GST also exhibits ligand-binding properties that initiate cellular apoptosis when triggered by cellular stress

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A blockage of ascorbate accumulation in response to high light was also observed when glutathione deficiency was induced pharmacologically by buthionine sulfoximine treatment, providing extra evidence that, in high-light conditions, glutathione acts as a substitute for ascorbate reduction (Figure 1)